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What’s the deal with the gut-brain connection?

March 10, 2025 By Parkinson's Community Help

Illustration of nutrients on a pathway to the brain
credit: Emily Moskal for Stanford Medicine

It affects your mood, your sleep, even your motivation to exercise. There’s convincing evidence that it’s the starting point for Parkinson’s disease and could be responsible for long COVID’s cognitive effects. And it sits about 2 feet below your brain.

The gut plays an obvious role in our health by digesting what we eat and extracting nutrients. But there’s a growing appreciation among scientists that our digestive systems affect our general well-being in a much broader fashion. One fascinating aspect of the gut’s widespread impact on health is its direct influence on and communication with the brain, a conduit known as the gut-brain axis.

SCOPE: What’s the deal with the gut-brain connection?

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