In this recent Movement Disorder Society hour-long podcast, well-known movement disorder specialist Dr. Stanley Fahn discusses the “most impactful paper” in movement disorders in the 20th century: the 1967 research article by George Kotzias, et al, about levodopa therapy. Dr. Fahn addresses the origins of levodopa therapy for PD in the 1960s and how that generated an explosion of interest and research in dopamine’s role in movement disorders.
Read Dr. Fahn’s article from August 2021 about the Kotzias paper