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Stanford’s SPRING study of gait in PD seeking participants who already have Medtronic DBS device

August 6, 2023 By Parkinson's Community Help

SPRING logo

The Human Motor Control and Neuromodulation Lab at Stanford University is seeking participants for the SPRING (Stanford Parkinson’s Research In Neuromodulation for Gait) Study.  The lab is looking for study participants who already have a Medtronic Percept PC model of deep brain stimulation (DBS) device.  Contact the lab today for details! 

The SPRING Study aims to investigate the safety and feasibility of adaptive deep brain stimulation (aDBS) for impaired gait and freezing of gait in Parkinson’s disease with the goal of advancing the development of patient-specific DBS therapy to improve quality of life for people living with Parkinson’s disease.  

Current DBS systems use open-loop stimulation, which means that stimulation is on all the time at a constant setting that does not change in response to a patient’s real-time state. This study is investigating the feasibility of a closed-loop system, or one that responds to your Parkinson’s symptoms and movement state in real time. 

These closed-loop settings will be investigated while you are in the Human Motor Control and Neuromodulation Laboratory. You will return to the open-loop settings programmed by a study doctor after the end of each in-lab research day. Optionally, if you elect to participate in our additional at-home testing, you may undergo closed-loop stimulation. 

Participants for the study:

  • Are between the ages of 18 and 80 years old
  • Are implanted with the Medtronic Percept PC device
  • Diagnosed with idiopathic Parkinson’s disease that is accompanied by gait impairment and/or freezing of gait.
  • Attend 4 research visits, lasting 3 – 4 days each, and occurring every 3 – 4 months.  
  • Participate in the study spanning approximately 1.5-2 years.  

For more information, contact the lab at (650) 723-6709. 

The principal investigator for this study is Helen Bronte Stewart, MD, MSE.

The study is sponsored by the National Institute of Health.  Study details are on clinicaltrials.gov.

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