Research Page 4 Stanford PD Community Blog

Join the Remote TOPAZ Clinical Trial Today

May 28, 2023 By Stanford Parkinson's Community Help

People with Parkinson’s disease or parkinsonism have a much higher risk of hip and other fractures. The TOPAZ (Trial of Parkinson’s and Zoledronic Acid) study will test if zoledronate, an FDA-approved medication for osteoporosis (thinning of the bone), can prevent fractures in people with Parkinson’s disease, whether or not they have osteoporosis. Using zoledronate for this purpose is investigational. Continue reading for a summary of the study and to see if you are eligible to participate. You could receive $100 upon enrollment and $50 per year during the study.

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Local TV News Story About Stanford’s Peter Tass, MD, Developing a Non-Invasive Treatment for PD

May 13, 2022 By Parkinson's Community Help

Dr. Peter Tass, a professor of neurosurgery at Stanford, has been developing a vibrating glove treatment for Parkinson’s Disease for decades. A local TV station recently talked to Dr. Tass about his research.

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Parkinson’s Progression Slower With Sustained Physical Activity

January 18, 2022 By Parkinson's Community Help

Man doing exercises — source: MedPageToday

More important to maintain exercise than to be active before disease starts, study shows

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Prediagnostic PSP – symptoms appear almost 8 years before diagnosis

January 15, 2022 By Parkinson's Community Help

This interesting study of “prediagnostic” progressive supranuclear palsy (PSP) out of the UK Biobank was recently published. It concludes that symptoms of PSP can be seen almost 8 years before diagnosis. Reaction time was the strongest predictive marker with changes evident as early as 10 years before diagnosis!
Note that no pathological confirmation of those with PSP was done for this study.

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Onset of Skin, Gut, and Genitourinary Prodromal Parkinson’s Disease: A Study of 1.5 Million Veterans

October 4, 2021 By Parkinson's Community Help

This interesting new research of 300,000 people with PD and 1.2 million matched controls explored prodromal Parkinson’s disease by studying the skin, genitourinary, and gastrointestinal issues reported. The researchers say that studying these systems “offers a unique window for understanding early disease pathogenesis and developing disease modifying treatments.”

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