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FDA’s New Warning: Link of Carbidopa/Levodopa to Vitamin B6 Deficiency and Seizures

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Vitamin B6
source: Freepik

On March 20, 2026, the U.S. Food and Drug Administration (FDA) issued a safety warning that requires products containing carbidopa/levodopa to carry new labeling which warns about the potential for Vitamin B6 (pyridoxine) deficiency. The warning guides physicians and other health care professionals to test for baseline vitamin B6 levels (with a blood test) prior to starting patients on treatment with carbidopa/levodopa therapies and periodically while on treatment and to supplement with vitamin B6 as necessary. Of note – it is important that patients do not take vitamin B6 on their own without monitoring blood levels, since vitamin B6 levels that are too high can be dangerous as well.

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“Employment and Parkinson’s: Rights and Protections,” Wednesday, April 22, 1pm PT – Register Now

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Register now for “Employment and Parkinson’s: Rights and Protections,” which will be of particular interest to the Young Onset Parkinson’s Disease (YOPD) community. This is the second installment of a three-part virtual lecture series featuring expert speakers and people with Parkinson’s, who address both practical and emotional challenges of YOPD.

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“El Parkinson y los tratamientos: ¿Qué hay de nuevo?” – Notas del webinar

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Natalie Diaz, MD
Natalie Diaz, MD

En febrero de 2026, la Parkinson’s Foundation presentó un webinar en español con la Dra. Natalie Díaz, neuróloga y especialista en trastornos del movimiento en Pacific Neuroscience Institute en Torrance, California, que también ha trabajado como investigadora en ensayos clínicos. La Dra. Díaz ofreció un panorama práctico de los tratamientos más recientes para la EP: nuevos medicamentos orales, dos terapias de infusión subcutánea y un tercer fármaco en espera de aprobación, además de avances en la estimulación cerebral profunda y el ultrasonido focalizado.

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Nutrition and Parkinson’s: Science, Strategies and What Really Matters – Webinar Notes

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Mediterranean diet
Mediterranean diet, source: Adobe Stock

In March 2026, the Davis Phinney Foundation hosted “Nutrition and Parkinson’s: Science, Strategies and What Really Matters”, a conversation with Richelle Flanagan, a registered dietitian and person with Parkinson’s, on evidence-based nutrition strategies for PD. Up to 90% of people with Parkinson’s don’t have access to a dietitian, yet nutrition plays a crucial role across the entire disease spectrum. The talk covered supplements, gut health, constipation, timing of medications with food, protein redistribution diets, and practical strategies. The fundamental message: eating better can help many people with Parkinson’s, but it requires proper dietary assessment and support rather than following trends online.

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