A recent drug trial by the UCSF Memory and Aging Center is the first of its kind for neurodegenerative disorders and represents an exciting new method for evaluating the effectiveness of a single drug on participants with the same underlying biology, but different diagnoses. First used in cancer research, basket trials lump together patients by disease pathology, not by diagnosis or symptoms. The UCSF trial evaluated the effectiveness of a drug, TPI-287, in treating toxic buildup of tau protein in the brains of patients with Alzheimer’s disease (AZ), corticobasal syndrome (CBS), and progressive supranuclear palsy (PSP). While the drug ultimately did not show promise, scientists still drew useful takeaways from the study, and future studies of neurodegenerative disease may benefit from utilizing a basket trial design.
… Full Story>Archives for 2019
NYT: Swimmers Beware of Deep Brain Stimulation
Excerpt: “Now, Dr. [Christian R.] Baumann warns all patients with stimulators never to go into deep water alone. … How the devices could interfere with swimming is not known. Dr. Baumann and his colleagues suggested that in some patients the signals may somehow affect a brain region that is crucial for coordinating limb movement. He said other complicated, learned skills might also be affected: Some patients said they could no longer ski after receiving stimulators, and one said he could not play golf anymore.”
… Full Story>December 2019 Webinars about Caregiving
Many caregivers cannot leave home due to caregiving responsibilities. You can participate in a web-based seminar — or webinar — from the privacy of your home. Join either live or view the archived version within a few day of the live webinar (in most cases). All webinars listed are free. All times shown are Pacific Time. Here are webinars that may be of interest to caregivers in December 2019…
… Full Story>December 2019 Webinars about Parkinson’s
You can participate in a web-based seminar — or webinar — from the privacy of your home. Join either live or view the archived version within a few days of the live webinar (in most cases). All webinars listed are free. All times listed are Pacific Time. Here are webinars that may be of interest to those living with Parkinson’s in December 2019…
Dec 2019 – Parkinson’s Support Group Mtgs – Guest Speakers/Programs – Northern and Central California
While most Northern and Central California Parkinson’s Disease (PD) support groups have holiday parties or are not meeting in December, a few groups do have meetings with speakers or programs. See the list below of what is happening near you…
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