Parkinson’s disease, which affects more than 10 million people worldwide, is a neurological disorder that occurs as a result of the death of nerve cells in the brain that produce dopamine. The loss of dopamine production in the brain can lead to tremors, balance problems, stiff facial expressions and muffled speech, among other things. How does Parkinson’s disease affect the body? The mind? How does having a progressive disease affect families? Listen to the stories of seven men and women with Parkinson’s disease.
ScienceDaily: New mechanism behind Parkinson’s disease revealed
Researchers have identified the precise toxic mechanism at work during an overabundance of the protein alpha-synuclein in neurons—the protein is a key causative agent in the development of Parkinson’s disease.
LiveScience: Dreams and Brain Disease: REM Sleep Cells Linked to Disorders
Where do dreams come from? Researchers now say they know: A specific group of cells in the brain stem is responsible for controlling dreaming sleep, also called Rapid Eye Movement (REM) sleep, a new study says…. Full Story>
New York Times: New Electrical Brain Stimulation Technique Shows Promise in Mice
Pulses of electricity delivered to the brain can help patients with Parkinson’s disease, depression, obsessive-compulsive disorder and possibly other conditions. But the available methods all have shortcomings: They either involve the risks of surgery, from implanting electrodes deep within the brain, or they stimulate from the skull’s surface, limiting the ability to target electricity to the right brain areas…. Full Story>
LIFE Shared This Remarkable Parkinson’s Disease Story in 1959. A Lot Has Changed Since Then

The great LIFE photographer Margaret Bourke-White was in Tokyo in 1952 when she first discovered that, in the middle of a physically demanding photojournalistic career, the dull pain in her left leg was becoming something more. Rising from a meal, she found herself, for a few steps at least, unable to walk.
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